Less than 1% of individuals using Tongkat Ali experience side effects. Learn how to mitigate these risks to ensure safe usage.

Less than 1% of individuals using Tongkat Ali experience side effects. Learn how to mitigate these risks to ensure safe usage.

Side Effects From Tongkat Ali Are Rare, Affecting Less Than 1% Of Users Worldwide. Over The Past 20 Years, No Reported Severe Side Effects Have Resulted In Hospitalisation Or Death From Consuming Pure 100% Tongkat Ali Extract.
Less than 1% of individuals using Tongkat Ali experience side effects. It is crucial to understand and mitigate these risks to ensure safe usage.

Side effects from Tongkat Ali are rare, affecting less than 1% of users worldwide. Over the past 20 years, no reported severe side effects have resulted in hospitalisation or death from consuming pure 100% Tongkat Ali extract.

However, individuals taking Tongkat Ali supplements from Huberman Lab, or Nootropics Depot have reported side effects such as irritability, insomnia, nausea, headaches, and swollen testes. These side effects indicate potential risks associated with Tongkat Ali.

Most reported side effects are primarily linked to Tongkat Ali supplements manufactured in the US, which may contain contaminants and impurities.

This article aims to provide valuable information to first-time Tongkat Ali users regarding the potential side effects, their likelihood of occurrence, and strategies to mitigate these risks.

Overview: Tongkat Ali Side Effects How You Can Apply Risk Mitigation

Tongkat Ali’s side effects range from mild to severe. Common side effects include headache, irritability, insomnia, elevated heart rate, anxiety, and gastrointestinal issues like nausea and diarrhea. Other possible side effects include changes in blood pressure, blood sugar levels, and liver toxicity. While some side effects are infrequent, others may occur more frequently in individuals allergic to bioactive compounds like alkaloids in Tongkat Ali.

Loss of appetite

It is common to experience a reduced appetite after consuming Tongkat Ali due to its cortisol-reducing effects. This should not be mistaken as a side effect, as it helps prevent emotional eating or overeating.

Likelihood: Common

Dizziness and Nausea

In rare cases, first-time users or those unaccustomed to herbal supplements may experience dizziness and nausea. This side effect tends to diminish after a few days. It may indicate an allergic or toxic reaction to Tongkat Ali if it persists. It is advisable to consult a doctor or healthcare professional in such cases.

Likelihood: Rare

Increased Heart Rate and Hypertension

High doses of Tongkat Ali (over 800mg) can cause heart palpitations due to increased metabolism. Individuals with chronic high blood pressure or pre-existing heart conditions should consult their doctors before using Tongkat Ali.

Likelihood: Rare


Tongkat Ali may cause restlessness, particularly in individuals with mild ADHD or undiagnosed anxiety. Feeling jittery or constantly uneasy indicates this minor side effect. It is more common in people sensitive to alkaloids, such as caffeine, or psychoactive substances.

Likelihood: Common among sensitive individuals


Tongkat Ali may worsen insomnia in individuals with mild or undiagnosed sleeping difficulties. While studies have shown that Tongkat Ali improves sleep quality, those experiencing insomnia should avoid its consumption before bedtime. Reducing coffee or tea intake while using Tongkat Ali may also mitigate this side effect.

Likelihood: Common among sensitive individuals

Anxiety, Panic Attacks and Depression:

Stimulants (alkaloids) present in Tongkat Ali may trigger anxiety and panic in some users. While Tongkat Ali generally elevates dopamine levels (happy hormones), it can have the opposite effect in individuals with mental health conditions, chronic depression, or anxiety.

Likelihood: Rare

Fatigue and Weakness

Tongkat Ali has been reported to cause fatigue in individuals with chronic fatigue syndrome. However, this side effect is scarce, as multiple clinical studies over the past 20 years have shown that Tongkat Ali boosts testosterone, energy, and stamina.

Likelihood: Extremely Rare

Skin Rash

Although extremely rare, some individuals may experience skin rashes after using Tongkat Ali, possibly due to allergy or hormone imbalance. Suppose a rash or other unexplained skin symptoms occur. In that case, Tongkat Ali usage should be discontinued, and a doctor should be consulted.

Likelihood: Extremely Rare

Diarrhea or Abdominal Pain

High doses of Tongkat Ali may lead to diarrhea or abdominal pain. While animal studies have shown localized DNA damage to stomach and duodenum tissue, no adverse side effects affecting humans have been reported in clinical studies.

Likelihood: Extremely Rare

Urinary Problems and Water Retention

In rare cases, users may experience urinary problems or edema (water retention) after consuming Tongkat Ali. This could be due to interactions with other medications. Swelling in the hands, feet, and legs may occur.

Likelihood: Extremely Rare

High/low Blood Sugar

Tongkat Ali can lower blood sugar levels, so individuals with diabetes or prediabetes should carefully monitor their blood glucose levels. Tongkat Ali should be cautiously used by individuals prone to hypoglycemia or taking medications that lower blood glucose.

Likelihood: Extremely Rare

Liver & Kidney

High doses of Tongkat Ali may affect the liver and kidneys, especially if impurities or toxic substances like mercury or lead are present in the extract. Using clinically tested Tongkat Ali products is advisable to minimize any potential adverse effects on the kidneys and liver. Individuals with pre-existing kidney or liver conditions should avoid Tongkat Ali supplementation.

Likelihood: Extremely Rare

Heart Palpitations

Although rare, some users may experience heart palpitations after consuming Tongkat Ali. This side effect can be mistaken for restlessness or jitteriness, particularly among first-time users. Reducing the dosage can help alleviate heart palpitations.

Likelihood: Rare


Side Effects Due to Drug Interaction

Numerous studies have examined the interaction of Tongkat Ali with various drugs. Tongkat Ali may interact with medications such as blood thinners, hypertension drugs, and diabetes medications.

For instance, the medicine Propranolol, used to treat heart problems, hypertension, anxiety, and migraines, can potentially cause side effects when taken alongside Tongkat Ali. However, a study published in the Journal of Clinical Pharmacy and Therapeutics found no significant changes in heart rate or blood pressure when combining Propranolol with Tongkat Ali.

It is essential to consult a physician or healthcare professional before using Tongkat Ali if you are currently taking medications, specifically Propranolol.

Likelihood: Varies depending on specific drug interactions

Reference: Salman et al., Journal of Clinical Pharmacy and Therapeutics (2010)




When it comes to Tongkat Ali, understanding the dosage and potential side effects is crucial for optimal usage. Finding the ideal balance that suits your body’s needs is essential to reap the benefits of this natural herb. This article will explore the recommended dosage, potential side effects, and factors to consider when choosing a Tongkat Ali supplement.


Major Causes of Tongkat Ali Side Effects

There are several potential causes of side effects from Tongkat Ali. These include overconsumption or excessive dosage, impurities or contaminants, high levels of mercury, arsenic or lead, lack of clinical testing, contamination, allergens, allergic reactions to alkaloids or quassinoids, and unknown drug interactions.

Dr Annie George, a lead scientist with 20 published papers on Tongkat Ali, emphasizes that pollutants, contaminants, and impurities significantly contribute to mild to severe side effects. Identifying the root causes of these side effects and taking necessary precautions to minimize risks is crucial.


Mitigating Side Effects of Tongkat Ali

To reduce the risk of side effects, it is recommended to consult with a healthcare provider before using Tongkat Ali and monitor for any adverse reactions, especially when taking other medications or supplements alongside Tongkat Ali.

If any adverse side effects occur, the following steps should be taken:

  1. Completely stop consuming Tongkat Ali.
  2. Lower the dosage to 100mg or less.
  3. Check for any potential drug interactions.
  4. Consult with a doctor or healthcare professional to discuss symptoms or side effects.


Optimal Dosage and Side Effects:

The dosage and duration of Tongkat Ali use play a significant role in determining the likelihood and severity of side effects. It is essential to avoid consuming a higher dosage than your body can tolerate, as this may lead to unwanted effects.

Researchers in the field recommend a daily dosage of Tongkat Ali between 200 to 400 milligrams, as supported by studies in Molecules and Healthline. However, it is essential to note that taking Tongkat Ali in the range of 50mg to 200mg per day has not shown any reported side effects.

Importance of Quality and Purity

Regarding Tongkat Ali supplements, not all products are created equal. The quality and purity of the supplement can significantly vary depending on the manufacturer. To ensure safe consumption, choosing a Tongkat Ali product that has undergone extensive clinical testing on both men and women is crucial. Look for lab-tested supplements for toxicity to guarantee their efficacy and safety.

Consulting with Healthcare Professionals

When considering incorporating Tongkat Ali into our daily routine, consulting with healthcare professionals is crucial. These experts possess the necessary knowledge and experience to guide us on the safest and most effective usage methods, ensuring optimal results for our circumstances.



Suppose you are taking any other medications alongside Tongkat Ali. In that case, consulting with your physician or healthcare professionals is vital. They can provide personalized guidance and ensure no potential interactions or adverse effects.

Tongkat Ali offers numerous benefits, but using it responsibly and adhering to the recommended dosage is essential. By understanding the optimal dosage range (200-400mg per day) and considering the quality and purity of the supplement, you can minimize the risk of experiencing any side effects. Prioritize your health and consult with healthcare professionals to ensure a safe and effective experience with Tongkat Ali.

Learn more about the benefits of Tongkat Ali and how it will improve your health and well-being.

Disclaimer: This article is for informational purposes only. The content does not replace professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health providers regarding specific health concerns or conditions.

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